Aparna made her acting debut in Yathra Thudarunnu (2013) and gained recognition with Maheshinte Prathikaaram (2016). She later starred in Sunday Holiday (2017), B. Tech (2018), and Sarvam Thaala Mayam (2018, Tamil). Her breakthrough came with Soorarai Pottru (2020), opposite Suriya, which earned her the National Film Award for Best Actress. In 2024, she appeared in Kishkindha Kaandam, further cementing her reputation as a versatile performer.