Aranthangi Nisha began her career as a stage performer and stand-up comedian in her hometown before entering television. She gained recognition through the comedy show Kalakka Povathu Yaaru and later became a household name with her appearances in Cooku with Comali and Bigg Boss Tamil Season 4. Her natural humor, strong personality, and ability to connect with audiences quickly made her one of the most loved comedians in Tamil entertainment.
She transitioned into films with supporting roles in movies like Maari 2 (2018), Kolamaavu Kokila (2018), and Kalakalappu 2 (2018). Beyond acting, Nisha is admired for her resilience and inspiring journey from a small town to mainstream cinema. She continues to balance her career in television, films, and live performances, while also being active on social media.