Darshan Jariwala began his career in Gujarati theatre before transitioning into Hindi television and films. His early work included popular TV serials like Kyunki Saas Bhi Kabhi Bahu Thi and Saans, where he became a familiar face in Indian households. His breakthrough in cinema came with Gandhi, My Father (2007), where his portrayal of Mahatma Gandhi was critically acclaimed and won him the National Film Award.
Over the years, Jariwala has appeared in a wide range of films such as Guru (2007), Aap Kaa Surroor (2007), Ajab Prem Ki Ghazab Kahani (2009), Raajneeti (2010), and Entertainment (2014). He has also been active in Gujarati cinema and theatre, continuing to balance mainstream Bollywood with regional projects. His ability to seamlessly move between serious roles and light-hearted characters has made him one of the most respected actors in the industry.