Niranjana Anoop made her acting debut in Loham (2015) directed by Ranjith. She later appeared in Puthan Panam (2017) alongside Mammootty, and in films like Kala Viplavam Pranayam (2018), Ira (2018), and B. Tech (2018). Apart from films, she has also acted in short films and web series, including Nagendran’s Honeymoons (2024). Her background in classical dance has shaped her artistic journey, and she continues to balance cinema with stage performances.