Sampada Hulivana began her career in television, making her debut in the Colors Kannada serial Mithuna Rashi. Her portrayal of Suraksha, a negative character, earned her recognition and helped her transition into films. She made her big-screen debut in Rider alongside Nikhil Kumaraswamy, where she played the second heroine. Her performance opened doors to Telugu cinema, where she acted in films like Sri Sri Sri Rajavaru and Mass Maharaju.
Currently, Sampada is working on Kannada films such as Karavali (2025) opposite Prajwal Devaraj and Ekka (2025) directed by Rohit Padaki. Known for her versatility, she has expressed interest in taking on more grounded and challenging roles. With her growing popularity, she is considered one of the promising young talents in Sandalwood.