Simone Singh began her career in the mid-1990s with television shows like Swabhimaan and Sea Hawks. She quickly became one of the most recognizable faces on Indian TV, starring in Heena (1998–2003), which made her a household name. Her elegant screen presence and versatility helped her transition into films, where she appeared in Kal Ho Naa Ho (2003), Being Cyrus (2005), and Ek Hasina Thi (2014).
Apart from acting, Simone has also hosted shows and worked as a model. She is admired for her sophisticated style and strong character portrayals, often playing layered roles in both television and cinema. More recently, she has appeared in digital projects, continuing to remain relevant in the evolving entertainment industry.