Ganesh started his career in the Tamil film industry with supporting and comedic roles, gradually becoming a recognizable face thanks to his distinct voice and witty timing. His breakthrough came with Gautham Vasudev Menon’s Vinnaithaandi Varuvaayaa (2010), where his portrayal of Simbu’s uncle was widely appreciated. This role not only brought him fame but also permanently associated him with the prefix “VTV.”
Since then, he has appeared in numerous films such as Endrendrum Punnagai (2013), Inga Enna Solluthu (2014), Achcham Yenbadhu Madamaiyada (2016), and Varisu (2023). Apart from acting, Ganesh has also produced films, including VTV. His career spans over two decades, and he continues to entertain audiences with his comedic timing and memorable screen presence.